PARACETAMOL Toxicity:usually occur within 2-3hours after ingestion of toxic doses of the drug
Nausea, vomiting and abdominal pain
Severe poisoning (blank) may occur initially
CNS stimulation, excitement and delirium
Best known form of hepatoxicity form
acetaminophen
hepatotoxicity is an acute, serious (blank) as a result of intentional or unintentional overdose
hepatocellular injury
PARACETAMOL preparation
acetylation
acetylation process
Preparation: (ESTERIFICATION
4-AMINOPHENOL
4-hydroxyaniline
4-AMINOPHENOL color of crystals
White or reddish-yellow crystals
4-hydroxyaniline White or reddish-yellow crystals or light brown powder that turns (blank) when exposed to light
violet
4-AMINOPHENOL Strong (blank) agent
reducing
2 forms:
Beta form (from acetone)
Alpha form on standing
exists as acicular crystals that turn into the; b) Alpha form on standing;
Beta form
hey are orthorhombic bipyramidal or pyramidal / beta-4-Aminopheno
Alpha form on standing
SYNTHESIS OF OXALIC ACID
CHEMICAL USED:
Nitric acid
Sucrose
NITRIC ACID
Aqua fortis
Spirits of niter
Eau forte
Hydrogen nitrate
Acidum nitricum
NITRIC ACID is a very what acid
A fuming acid
Very what?
caustic
nitric acid odor
Highly irritating odor
NITRIC ACID is Miscible with
water