Study Set Content:
an electron acceptor for the enzymes isocitrate dehydrogenase, α- ketoglutarate dehydrogenase, and malate dehydrogenase
Niacin
NIACIN, in the form of
NAD (nicotinamide adenine dinucleotide
the coenzyme for the decarboxylation in the α-ketoglutarate dehydrogenase reaction.
THIAMINE
THIAMINE, as
thiamine diphosphate
he cofactor attached to acetyl CoA and succinyl CoA
PANTOTHENIC ACID,
as part of
coenzyme A (CoA
However, before the citric acid cycle can begin, (blank) must be produced
Acetyl CoA
However, before the citric acid cycle can begin, acetyl CoA must be produced. Acetyl CoA is created from
pyruvate
However, before the citric acid cycle can begin, acetyl CoA must be produced. Acetyl CoA is created from pyruvate (the end product of glycolysis) during
pyruvate oxidation.
Pyruvate oxidation results
e molecule of acetyl CoA, one molecule of carbon dioxide, and one molecule of NADH.
Pyruvate
Oxidation reaction
Acetyl CoA
Reaction 1 enzyme involved
Citrate Synthase
In this step, oxaloacetate is joined with
acetyl-CoA
In this step, oxaloacetate is joined with acetyl-CoA to form
citric acid
Once the two molecules are joined, a (blank) attacks
water molecule
nce the two molecules are joined, a water molecule attacks the acetyl leading to the
release of CoA from the complex.
Reaction 2 enzyme
aconitase
In this reaction, a (blank) is removed from the citric acid and then put back on in another location
water molecule
