• A chemical substance produced by a microorganism which has the capacity to inhibit the growth of or to kill other microorganisms
ANTIBIOTICS
ANTIBIOTICS From the greek word
“antibiosis
“anti” –
– against
“bios
– life
Literally means “against life”
ANTIBIOTICS
Antibiotics are used to treat infections caused by
Bacteria
Bacteria are microscopic organisms, some of which may cause illness
illness
it inhibits the growth or multiplication of bacteria.
Bacteriostatic
Bacteriostatic examples
Chloramphenicol, erythromycin, clindamycin, sulfonamides, trimethoprim, tetracyclines
- it destroys or kills bacteria.
Bactericidal
Ex.
Aminoglycosides, beta-lactams, vancomycin, quinolones, rifampin metronidazole
These substances target microorganisms such as
bacteria, fungi and parasites.
Antibiotics works by affecting things that bacterial cells have but human cells
don't
Antibiotics do not fight infections caused by () such as:
viruses
Antibiotics do not fight infections caused by viruses such as:
colds, flu, most cough & bronchitis, sore throat
Before fleming introduced to the world about penicillins in 1928, he discovered
LYSOZYME
Before fleming introduced to the world about penicillins in 1928, he discovered lysozyme first in
1920
Before fleming introduced to the world about penicillins in 1928, he discovered lysozyme first in 1920. • But like (), the drugs toxicity precluded its use
pyocyanase
8 years after lysozyme was introduced, in () () was discovered
1928, penicillins
The 1st identitified chemical compound with antibiotic properties _ considered to be the first “true antibiotic “
PENICILLINS