Study Set Content:
STREPTOMYCIN IS THE FIRST LINE OF CHOICE FOR THE TREATMENT OF TUBERCULOSIS (Mycobacterium tuberculosis), combined with
ethambutol and isoniazid
Streptomycin has some value in controlling
Yersinia pestis (plague) and Francisella tularensis (tularemia),
Streptomycin has some value in controlling Yersinia pestis (plague) and Francisella tularensis (tularemia), combined with
sulphonamide.
Streptomycin is also indicated in bacterial endocarditis in combination with() and also in brucellosis in combination with ()
penicillin, tetracycline.
AN AMINOGLYCOSIDE ANTIBIOTIC ISOLATED FROM Streptomyces fradiae in 1949.
NEOMYCIN
ISOLATED FROM S. rimosus
PAROMOMYCIN
a mixture of 3 antibiotic compounds, neomycin
A, B, C
IS THE MAIN COMPONENT OF THE MIXTURE)
NEOMYCIN B
a mixture of 2 diff.antibiotics
aromomycins I & II
WAS ISOLATED FROM Streptomyces kanamayceticus in 1957
• KANAMYCIN
a mixture of 3 aminoglycoside antibiotics, that contains 2 aminosugars that are linked individually to a 2- deoxy-streptamine aglycone.
KANAMYCIN
It is used orally for control of infections & for preoperative treatment.
KANAMYCIN
Kanamycin can be used parenterally for treatment of serious () when susceptible strains are involved
gr (-) infections
IS PRODUCED BY Micromonospora purpurea (an actinomycete).
GENTAMICIN
It consists of a mixture o
C1, C1A & C2
is the major component)
C1
It contains 2 aminosugar residues and a 2- deoxystreptamine unit
GENTAMICIN
Effective against many gram-negative bacteria, especially Pseudomonas species, as well as certain gram-positive species • Used as the sulphate salt
GENTAMICIN
TOBRAMYCIN OR
NEBRAMYCIN FACTOR 6
THE SINGLE-COMPONENT ANTIBIOTIC THAT IS SEPARATED FROM THE NEBRAMYCIN COMPLEX PRODUCED BY Streptomyces tenebrarius.
TOBRAMYCIN
