Study Set Content:
Substances released during(blank)mediated
immune reactions that activate the complement cascade
also release histamine from mast cells and basophils.
IgG- or IgM-
By a negative feedback control mechanism mediated by
(blank), histamine appears to (blank) its own
release and that of other mediators from sensitized mast
cells in some tissues.
H2 receptors, modulate
FIVE CLASSES OF IMMUNOGLOBULINS
IgM
IgG
IgA
IgD
IgE
Pentamer(IgM)
IgG
(monomer) IgD and IgE
Dimer IgA
are the first circulating antibodies to appear
in response to an initial exposure to an antigen:
their concentration in the blood declines rapidly,
IgMs
IgMs are the first circulating antibodies to appear
in response to an initial exposure to an antigen:
their concentration in the blood declines rapidly,
Thus the presence of IgM usually indicates a
current infection
IgMs are the first circulating antibodies to appear
in response to an initial exposure to an antigen:
their concentration in the blood declines rapidly,
Thus the presence of IgM usually indicates a
current infection. IgM consists of (blank) arranged in a pentagon structure. The
numerous antigen-binding sites make it very
effective in agglutinating antigens and in reactions
involving complement.
five Y-shaped
monomers
is too large to cross the
plaenta and does not confer maternal immunity.
IgM
is the most abundant of the circulating
antibodies. It readily crosses the walls of blood
vessels and enters tissue fluids.
IgG
also crosses
the placenta and confers passive immunity on the
fetus. protects against bacteria, viruses, and
toxins in the blood and lymph, and triggers action
of the complement system.
IgG
is produced by cells in mucous membrane.
IgA
The
main function of IgA is to prevent the attachement
pf viruses and bacteria to
epithelial surfaces.
is
also found in many body secretions, such as saliva,
perspiration, and tears.
IgA
Its presence in the first
(blank) produced helps protect the infant from
gastrointestinal infections.
milk
antibodies do not activate the complement
system and cannot cross the placenta.
IgD
They are
mostly found on the surfaces of
B cells,
They are
mostly found on the surfaces of B cells, probably
functioning as antigen receptors that help initiate
the differentiation of B cells into plamsa cells and
memory B cells.
IgD
molecules are slightly larger than IgG and
represent only a small fraction of the antibodies in
the blood.
IgE
