Study Set Content:
61- Flashcard

benzodiazepines (including

chlordiazepoxide) [Librium]

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diazepam

[Valium

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carbamate meprobamate

 [Miltown

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based on random screening of newly synthesized chemicals.

carbamate meprobamate [Miltown])

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Psychopharmacologic agents

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The discovery of these drugs was based on observations of effects on the behavior of animals used in screening

bioassays

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Chlorpromazine HCl

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Chlordiazepoxide HCl

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Meprobamate Milltown

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observed unusual and characteristic paralysis and relaxation of voluntary muscles in laboratory animals for different series of compounds.

Frank M. Berger

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At this point, the treatment of ambulatory anxious patients with

meprobamate

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 psychotic patients with one of the

aminoalkylphenothiazine drugs

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Structural modifications of benzodiazepine derivatives were undertaken, and a compound 5 to 10 times more potent than chlordiazepoxide was synthesized in 1959 and marketed as

diazepam (Valium)

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are used in the pharmacotherapy of anxiety and related emotional disorders and in the treatment of sleep disorders, status epilepticus, and other convulsive states.

Benzodiazepines

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they are used as centrally acting muscle relaxants, for premedication, and as inducing agents in anesthesiology.

Benzodiazepines

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Steroidal agents

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Progesterone

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Norethynodrel

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Norethindrone

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80- Flashcard

Mestronol

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