Specifically,the 3-OH of the sugar moiety of one nucleotideisesterified to a phosphate group, whichis, inturn,joined to the
5-OH of the adjacent sugar
Each heterocyclic base bonds to the anomericcarbon(C1') of the ribose or deoxyribose ring with a
β-C-N-glycosidic bond
bicyclic base with fused five andsix-membered rings
Purine
Adenine (A):
: 6–amino-purine
Guanine (G):
2–amino–6-oxypurine
monocyclic base with six-membered ring
Pyrimidine:
Thymine (T
: 2,4–dioxy–5–methylpyrimidine
Cytosine (C):
: 2–oxy–4-aminopyrimidine
Uracil (U):
2,4-dioxypyrimidine
Purine
adenine
Guanine
Cytosine
pyrimidine
Thymine
Uracil
It is the sequence of these bases that stores the
genetic information
The nitrogen and oxygen atoms present on the nitrogen bases provide a number of sites where
hydrogen bonding is possible.
Hydrogen bonding is most effective and easily formed between certain combinations of
nitrogen bases
Hydrogen bonding is most effective and easily formed between certain combinations of nitrogen bases. Because of this, certain combinations will form, and it is this pattern that is responsible for the
transmission of information.