Components of membrane
(impart fluidity and pliability)
acts as surfactant and lowers the surface tension in alveoli of lungs
Dipalmitoyl lecithin
absence of lecithin in premature infants
Respiratory distress syndrome
(e.i. inositol triphosphate and diacylglycerol)
Intracellular signals
Anchors proteins to
cell membrane
Phospholipids Solubilzation of
Cholesterol
Phospholipids Transport of lipids via
lipoproteins
Also called phosphoglycerides
Glycerophospholipids
Membrane components of cells throughout the body
Glycerophospholipids
– Alcohol is
Glycerol
Two groups are esterified by
fatty acids
The fatty acid on carbon 2 is
unsaturated
is esterified by a phosphate group which is esterified to another alcohol
Third group
are present in cell membranes; major component in egg yolk; are excellent emulsifier and is used in mayonnaise
Phosphatidylcholine (lecithins):
Phosphatidylcholine alcohol
choline
is important in nervous transmission as acetylcholine.
Choline
similar to lecithins except that instead of choline, they contain other alcohols, such as ethanolamine or serine;
Cephalins
found in cell membranes; phosphatidylserine plays a role in
apoptosis (programmed cell death/cell suicide)
Phosphatidylethanolamine
Phosphatidylserine