Study Set Content:
Composed of relatively few amino acids; water-soluble
Peptides
Hydrolytic products which have simpler structures than proteoses; soluble in water
Peptones
Decomposition of proteins to amino acid
PROTEINS-proteans-metaproteins-proteoses-peptones-peptides-amino acids
• The primary structure of a protein is simply the sequence o
amino acids comprising the molecule.
• All proteins have a primary structure because all proteins by definition consist of a sequence of
amino acids
The primary structure serves as the foundation upon which all higher levels of
protein structure build.
H3N amino end
amino acid subunits
• It is possible for one peptide bond to form a hydrogen bond to another
peptide bond
e α-helix, the primary structure twists into a tightly wound
spring or rod-like structure.
In the β-pleated sheet, or simply the β sheet, the primary structure is (blank) instead of tightly winding into a helix.
extended
is simply a bend in the primary structure held in place by a hydrogen bond.
hairpin bend
gets its name because of the loose similarity of its shape to the Greek letter.
Ω-loop
• Both are found on the
exterior of proteins.
The overall shape of a protein is determined by its primary and secondary structures along with interactions between the
side chains
The overall shape of a protein is determined by its primary and secondary structures along with interactions between the side chains. • This gives rise to what is called the protein’s
tertiary structure.
Tertiary structure
1. Covalent bonds
2. Hydrogen bonding
3. Salt bridges (electrostatic attractions)
4. Hydrophobic interactions
5. Metal ion coordination
Elements of tertiary structure of proteins
1. disulfide bonds
2. hydrogen bonds
3.salt bridges
4.hydrophobic interactions
disufide bonds
salt bridges
