• An agent intended for use in the diagnosis, mitigation, treatment, cure, or prevention of disease in humans or in other animals.
Drug
• One of its most astounding qualities is the diversity of their actions and effects on the body.
Drug
• The use of drugs predates recorded human history in man’s efforts to relieve pain and suffering, recover from injury, and extend life.
Drug
Drugs have existed as long as humans. Their discovery was led by
human disease and the instinct to survive.
– More than 800 formulas or prescriptions
Ebers papyrus
More than 700 drugs mentioned
Ebers papyrus
Early Drugs
• Ebers papyrus
• Botanical
• Mineral
• Animal
• Vehicles used
Hippocrates
(ca. 460–377 BC)
• Dioscorides
(first century AD)
Galen
(ca. 130–200 AD)
Emperor Frederick II,
1240 AD
Paracelsus
(1493–1541 AD)
Father of Medicine
Hippocrates
Pharmacognosy
Dioscorides
“Galenic pharmacy.”
Galen
Introduction of the Scientific Viewpoint
• Hippocrates
• Dioscorides
• Galen
• Emperor Frederick II
• Paracelsus
– discovered Lactic acid, citric acid, oxalic acid, tartaric acid, arsenic acid, glycerin, calomel, benzoic acid, oxygen
• Karl Wilhelm Scheele
in 1805 isolated morphine from opium
• Friedrich Serturner
Quinine, cinchonine, and brucine
Joseph Caventou and Joseph Pelletier
Early Research
• Karl Wilhelm Scheele
• Friedrich Serturner
• Joseph Caventou and Joseph Pelletier