Study Set Content:
Oligomycin is a macrolide antibiotic synthesized by Streptomyces species that inhibits the
F0 subunit
Oligomycin is a macrolide antibiotic synthesized by Streptomyces species that inhibits the F0 subunit of
ATP synthase,
Oligomycin is a macrolide antibiotic synthesized by Streptomyces species that inhibits the F0 subunit of ATPsynthase, preventing
ATP production.
• Oligomycin is a macrolide antibiotic synthesized by Streptomyces species that inhibits the F0 subunit of ATP synthase, preventing ATP production. Its predominant use is for
research purposes
The Pentose Phosphate Pathway• also called the
phosphogluconate pathway and the hexose monophosphate shunt
The pentose phosphate pathway (PPP) branches from
glucose 6-phosphate (G6P
e pentose phosphate pathway (PPP) branches from glucose 6-phosphate (G6P), produces
NADPH and ribose 5-phosphate
The pentose phosphate pathway (PPP) branches from glucose 6-phosphate (G6P), produces NADPH and ribose 5-phosphate (R5P), and shunts carbons back to the
glycolytic or gluconeogenic pathway
It does not lead to the formation of ATP, rather Formation of
NADPH
it does not lead to the formation of
ATP
It does not lead to the formation of ATP, rather • Formation of NADPH for the synthesis of
fatty acids and steroids
Synthesis of
ribose for nucleotide and nucleic acid formation
The Pentose Phosphate Pathway occurs in the
cytosol
is responsible for converting the intermediate glucose-6-phosphate to 6-phosphogluconat
oxidative phase
The oxidative phase is responsible for converting the intermediate
glucose-6-phosphate
The oxidative phase is responsible for converting the intermediate glucose-6-phosphate to
o 6-phosphogluconate
• The oxidative phase is responsible for converting the intermediate glucose-6-phosphate to 6-phosphogluconate, using the
glucose-6-phosphate dehydrogenase enzyme
The by-product of this reaction is the important molecule
NADPH
6-phosphogluconate then converts into
ribulose-5-phosphate
The by-product of this reaction is the important molecule NADPH. 6-phosphogluconate then converts into ribulose-5-phosphate, and (blank) gets produced again as a by-product
NADPH
