Study Set Content:
When a nicotinic agonist is applied directly (by iontophoresis or by intra-arterial injection), an immediate _____ of the end plate results, caused by an increase in permeability to sodium and potassium ions.
depolarization
Contraction (miosis)
Sphincter muscle of iris
Contraction for near vision (accommodation)
Ciliary muscle
Decrease in rate (negative chronotropy)
Sinoatrial node
Decrease in contractile strength (negative inotropy). Decrease in refractory period
Atria
Decrease in conduction velocity (negative dromotropy). Increase in refractory period
Atrioventricular node
Small decrease in contractile strength
Ventricles
Dilation (via EDRF). Constriction (high-dose direct effect)
Arteries, veins
Contraction (bronchoconstriction
Bronchial muscle
Secretion
Bronchial glands
Increase
Motility
Relaxation
Sphincters
Stimulation
Secretion
Contraction
Detrusor
Relaxation
Trigone and sphincter
Secretion
Sweat, salivary, lacrimal, nasopharyngeal
PHYSIOLOGIC ACTIONS OF ACETYLCHOLINE
(ACH)
Gastrointestinal system (blank) motility of the GIT and bladder
increase
Pulmonary system it (blank) secretions of the bronchioles
increases
The eye causes (blank) of the pupillary sphincter muscle, which causes miosis and accommodation.
constriction
Cardiovascular system it decreases .
heart rate, contractility, and blood pressure
